Score a 5 on AP Biology: The Only 2025-2026 Guide You'll Ever Need

AP Biology Study Guide: 2025-2026 Edition

AP Biology Study Guide: 2025-2026 Edition

Comprehensive AP Biology Curricular and Assessment Framework for the 2025–2026 Academic Year. Master the four Big Ideas, unit content, exam strategies, and laboratory investigations.

๐Ÿ“– Est. reading time: 120 minutes ๐Ÿ”„ Last updated: January 2026
Modern scientific laboratory with advanced research equipment
1

Introduction to AP Biology

Understanding the 2025-2026 Exam Format and preparing effectively for success in AP Biology.

Understanding the 2025-2026 Exam Format
  • ๐Ÿ”„Digital Transformation: Section I (60 MCQs) administered via Bluebook app with enhanced tools
  • ๐Ÿ“Hybrid Format: Section II (6 FRQs) combines digital prompts with handwritten responses
  • ⏱️Timing: 90 minutes each section, 50% weight for each
  • ๐Ÿ“ŠScoring: Nearly 70% achieve 3+ for college credit
Section Format Duration Weight
Section I: Multiple-Choice 60 Questions (Digital/Bluebook) 90 minutes 50%
Section II: Free-Response 6 Questions (2 Long, 4 Short - Hybrid) 90 minutes 50%
Timeline for Preparation
  • ๐Ÿ“…Year-long: Build unit-by-unit understanding with consistent practice
  • ๐ŸŽฏ6 months: Focus on integrated review emphasizing weak units
  • 3 months: Intensive practice with full-length exams and skill work
  • ๐Ÿ”ฅFinal week: High-yield concept review and formula memorization

Study Tip for Introduction

Familiarize yourself with Bluebook digital tools early—practice annotation, highlighting, and flagging features.

Success in AP Biology requires balancing content mastery with analytical skills. The four Big Ideas provide the framework for understanding how biological systems interconnect and evolve.

๐Ÿ“Š Your AP Biology Mastery Progress

Introduction
Big Ideas
Unit 1
Unit 2
Unit 3
Unit 4
Unit 5
Unit 6
Unit 7
Unit 8
Labs
Exam Prep

๐ŸŽฏ Week 1 Challenge: Master the Exam Format

Complete this task to earn your first mastery badge:

Format Expert

Task: Download Bluebook app, complete a practice MCQ section, and write a 200-word reflection on how digital tools enhance biology assessment. Share with #APBio2026

๐ŸŽฅ Recommended Starting Video

Watch this Khan Academy AP Biology overview: Khan Academy AP Biology Playlist

Four interconnected biological concepts representing evolution, energy, information, and systems
2

The Four Big Ideas of AP Biology

The four Big Ideas serve as connective tissue between all units, providing the framework for understanding biological systems.

Big Idea 1: Evolution (13-20% of exam - Most Weighted)
  • ๐Ÿ”„Natural Selection: Variation, heritability, differential survival/reproduction
  • ๐Ÿ“ŠHardy-Weinberg: p + q = 1 and p² + 2pq + q² = 1 (five conditions)
  • ๐Ÿฆ Evidence: Fossil record, comparative anatomy, molecular clocks
  • ๐ŸŒฟSpeciation: Allopatric vs. sympatric, reproductive isolation
Big Idea 2: Energy and Molecular Building Blocks (12-16% of exam)
  • Cellular Respiration: Glycolysis, Krebs cycle, electron transport chain
  • ☀️Photosynthesis: Light-dependent reactions, Calvin cycle
  • ๐ŸงฌEnzymes: Active site, environmental effects, reaction rates
  • ๐Ÿ”‹ATP: Energy currency, coupled reactions
Big Idea 3: Information Storage and Transfer (12-16% of exam)
  • ๐ŸงฌDNA Replication: Semi-conservative, leading/lagging strands
  • ๐Ÿ“–Central Dogma: DNA → RNA → Protein (transcription, translation)
  • ๐ŸŽญGene Regulation: Operons, epigenetics, transcription factors
  • ๐ŸงซBiotechnology: PCR, CRISPR, gel electrophoresis
Big Idea 4: Systems Interactions (10-15% of exam)
  • ๐Ÿ“กCell Communication: Signal transduction, receptors, amplification
  • ⚖️Feedback Mechanisms: Negative vs. positive feedback
  • ๐Ÿ›ก️Immune System: Innate vs. adaptive responses
  • ๐ŸŒEcology: Energy flow, nutrient cycling, community interactions

Study Tip for Big Ideas

Use the Big Ideas as lenses to connect concepts across units—evolution explains both diversity and unity of life.

Biology textbook and study materials showing detailed unit breakdowns
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Unit-by-Unit Content Breakdown

Detailed coverage of all eight AP Biology units with key concepts, formulas, and study tips.

Unit 1: Chemistry of Life (6-9% of exam)
  • ⚗️Core Elements: C, H, O, N, P, S (sulfur elevated in 2025 CED)
  • ๐Ÿ’งWater Properties: Polarity, cohesion, adhesion, thermal buffer
  • ๐ŸงฌMacromolecules: Carbohydrates, lipids, proteins, nucleic acids
  • ๐Ÿ”—Synthesis: Dehydration vs. hydrolysis reactions
Unit 2: Cell Structure and Function (10-13% of exam)
  • ๐Ÿ“Surface Area to Volume: SA:V ratio limits cell size
  • ๐ŸงซProkaryotic vs. Eukaryotic: Nucleus, organelles, size differences
  • ๐Ÿ”ฌMembrane Structure: Fluid mosaic model, selective permeability
  • ๐ŸšชTransport: Passive (diffusion, osmosis) vs. active transport
Unit 3: Cellular Energetics (12-16% of exam - Heavily Weighted)
  • ๐ŸงชEnzymes: Active site, environmental effects, kinetics
  • Cellular Respiration: Glycolysis, Krebs, ETC, fermentation
  • ☀️Photosynthesis: Light reactions, Calvin cycle, factors affecting rate
  • ๐Ÿ”„ATP: Energy coupling, conservation of glycolysis
Unit 4: Cell Communication and Cell Cycle (10-15% of exam)
  • ๐Ÿ“กSignal Transduction: Reception, transduction, response, amplification
  • ๐Ÿ”„Cell Cycle: Interphase (G₁, S, G₂), mitosis, cytokinesis
  • ๐ŸŽฏRegulation: Cyclins, CDKs, checkpoints, cancer
  • ๐ŸงฌMitosis vs. Meiosis: Purpose, products, genetic variation
Unit 5: Heredity (8-11% of exam)
  • ๐ŸงฌMeiosis: Genetic variation through crossing over, independent assortment
  • ๐Ÿ‘ฅMendelian Genetics: Dominance, probability rules, pedigrees
  • ๐ŸŽญNon-Mendelian: Incomplete dominance, codominance, pleiotropy
  • ๐ŸŒฟEnvironmental Influence: Phenotypic plasticity
Unit 6: Gene Expression and Regulation (12-16% of exam - Heavily Weighted)
  • ๐Ÿ“–Central Dogma: Replication, transcription, translation
  • ๐ŸŽญGene Regulation: Prokaryotic operons, eukaryotic controls
  • ๐ŸงซBiotechnology: PCR, CRISPR, sequencing, electrophoresis
  • ๐Ÿ”„Mutations: Types, effects, chromosomal changes
Unit 7: Natural Selection (13-20% of exam - Most Heavily Weighted)
  • ๐Ÿ”„Hardy-Weinberg: Equilibrium conditions, calculations
  • ๐ŸŽฏMechanisms: Natural selection, genetic drift, gene flow, mutation
  • ๐Ÿฆ•Evidence: Fossils, anatomy, molecular, biogeography
  • ๐ŸŒฟSpeciation: Allopatric vs. sympatric, isolation mechanisms
Unit 8: Ecology (10-15% of exam)
  • ๐Ÿ“ˆPopulation Dynamics: Exponential vs. logistic growth
  • ๐ŸคCommunity Interactions: Competition, predation, symbiosis
  • Energy Flow: Trophic levels, pyramids, productivity
  • ♻️Nutrient Cycling: Carbon, nitrogen, phosphorus, water

Study Tip for Units

Focus heavily on Units 3, 6, and 7—they account for over 50% of exam questions combined.

Scientific data analysis and graphing techniques for biology
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Essential Skills and Science Practices

Master the six Science Practices that are assessed throughout the exam.

The Six Science Practices (25-33% of MCQs)
  • 1️⃣Concept Explanation: Explain biological processes in applied contexts
  • 2️⃣Visual Representations: Analyze diagrams, graphs, models
  • 3️⃣Questions and Methods: Design experiments, identify variables
  • 4️⃣Representing Data: Construct and label graphs/tables
  • 5️⃣Statistical Tests: Perform calculations, analyze data
  • 6️⃣Argumentation: Develop evidence-based scientific claims
Science Practice 2: Visual Representations
  • ๐Ÿ“ŠReading Graphs: Identify variables, trends, outliers
  • ๐Ÿ”ฌInterpreting Models: Cellular structures, pathways, phylogenies
  • ๐Ÿ“ˆGraph Types: Line, bar, scatter plots, histograms
Science Practice 3: Questions and Methods
  • Hypothesis: Testable prediction based on prior knowledge
  • ๐Ÿ”ฌVariables: Independent, dependent, constants, controls
  • ๐Ÿ“Experimental Design: Replicates, reliability, validity

Study Tip for Science Practices

Practice Science Practices 2 and 6 regularly—they appear frequently in both MCQs and FRQs.

Mathematical equations and biological calculations for AP Biology
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Mathematical Skills and Formulas

Master the quantitative aspects of AP Biology with key formulas and calculations.

Official Equations and Formulas Sheet
Statistical Analysis: Sample Mean: x̄ = (ฮฃxแตข)/n Standard Deviation: s = √[ฮฃ(xแตข - x̄)²/(n-1)] Standard Error: SE = s/√n Chi-Square: ฯ‡² = ฮฃ[(o-e)²/e] Genetics: Hardy-Weinberg: p + q = 1 and p² + 2pq + q² = 1 Probability: P(A or B) = P(A) + P(B); P(A and B) = P(A) × P(B) Water Potential: ฮจ = ฮจโ‚› + ฮจโ‚š Solute Potential: ฮจโ‚› = -iCRT Surface Area & Volume: Sphere: SA = 4ฯ€r², V = (4/3)ฯ€r³ Cube: SA = 6s², V = s³ Population Growth: Exponential: dN/dt = r_max N Logistic: dN/dt = r_max N((K-N)/K) Biodiversity: Simpson's Index: D = 1 - ฮฃ(n/N)²
Problem-Solving Strategies
  • ๐Ÿ“–Read carefully: Identify what's being asked
  • ๐Ÿ”Identify knowns and unknowns
  • ๐ŸงฎChoose appropriate formula and plug in values
  • Check reasonableness and units

Study Tip for Math

Practice calculations daily—focus on Hardy-Weinberg, water potential, and chi-square problems.

Biology laboratory experiments and scientific research
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Laboratory Investigations

Master the 13 required investigations that form the foundation for experimental questions.

The 13 Required Investigations
  • 1️⃣Artificial Selection: How selective pressure changes traits
  • 2️⃣Hardy-Weinberg: Mathematical modeling of evolution
  • 3️⃣BLAST: Comparing DNA sequences across species
  • 4️⃣Diffusion and Osmosis: Factors affecting cell transport
  • 5️⃣Photosynthesis: Light effects on energy capture
  • 6️⃣Cellular Respiration: Temperature effects on metabolism
  • 7️⃣Cell Division: Stimuli impact on mitosis
  • 8️⃣Transformation: Genetic modification of bacteria
  • 9️⃣Restriction Analysis: DNA visualization techniques
  • ๐Ÿ”ŸEnergy Dynamics: Flow through trophic levels
  • 1️⃣1️⃣Transpiration: Environmental effects on water loss
  • 1️⃣2️⃣Fruit Fly Behavior: Stimuli triggering movements
  • 1️⃣3️⃣Enzyme Activity: Conditions affecting catalysis
Critical Lab Concepts
  • ๐Ÿ”ฌExperimental Design: Hypothesis, variables, controls, replicates
  • ๐Ÿ“ŠData Collection: Quantitative vs. qualitative data
  • ๐ŸงซLab Safety: Proper techniques and disposal

Study Tip for Labs

At least 25% of instructional time must be hands-on lab work—understand variables and controls deeply.

Study techniques and learning methods for academic success
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Study Strategies and Techniques

Effective study methods for mastering AP Biology content and skills.

Active Learning Methods
  • ๐Ÿง Concept Mapping: Visual connections between Big Ideas
  • ๐ŸŽคFeynman Technique: Teach concepts in simple terms
  • ๐Ÿ“Practice Problems: 5-10 daily, focus on calculations
  • ๐ŸŽดFlashcards: Spaced repetition for vocab and formulas
Time Management
  • ๐Ÿ“…12 weeks out: Content review (1-2 units/week)
  • ๐ŸŽฏ8 weeks out: Practice FRQs and MCQs
  • 4 weeks out: First full-length practice exam
  • ๐Ÿ”ฅFinal week: Review weak areas, formula memorization

Study Tip for Strategies

Dedicate 25% of study time to hands-on lab understanding and Science Practices.

Exam preparation and test-taking strategies for academic success
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Test-Taking Strategies

Master MCQ and FRQ strategies for optimal performance on the AP Biology exam.

Multiple Choice Tips (Section I)
  • ⏱️Time Management: 1.5 minutes per question, use flag feature
  • ๐Ÿ”Process of Elimination: Cross out wrong answers first
  • ๐Ÿ“ฑBluebook Tools: Annotation, highlighting, flagging
  • ๐ŸŽฏEducated Guessing: Always guess, no penalty
Free Response Tips (Section II)
  • ⏱️Time Allocation: 23 min long FRQs, 11 min short FRQs
  • ๐Ÿ“Reading Prompts: Underline task verbs, number parts
  • Show Work: Calculations need all steps for partial credit
  • ๐ŸŽจLabel Diagrams: Complete labeling earns full points

Study Tip for Test-Taking

Avoid "science vomit"—address only what the task verb asks for.

Educational resources and study materials for academic success
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Resources and Tools

Essential study materials and online resources for AP Biology preparation.

Official College Board Resources (FREE)
  • ๐Ÿ“–Course and Exam Description (CED): Complete curriculum
  • ๐ŸŽฏAP Classroom: Practice questions and progress checks
  • ๐Ÿ“Released FRQs: Past free-response questions
  • ๐ŸงฎEquations Sheet: Official formulas provided
Recommended Study Materials
  • ๐Ÿ“šCampbell Biology: Comprehensive college textbook
  • ๐Ÿ“–Barron's AP Biology: Practice tests and review
  • ๐ŸŽฅKhan Academy: Free videos and practice
  • ๐Ÿ“ฑQuizlet/Anki: Spaced repetition flashcards

Study Tip for Resources

Use College Board resources first—they're free and directly aligned with the exam.

Quick reference charts and diagrams for biology study
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Quick Reference Section

Essential vocabulary, formulas, and diagrams for quick review.

Key Vocabulary by Unit
Unit Key Terms
Unit 1 Hydrogen bonding, cohesion, adhesion, dehydration synthesis, hydrolysis
Unit 2 Prokaryote, eukaryote, selective permeability, osmosis, diffusion
Unit 3 Enzyme, active site, photosynthesis, cellular respiration, ATP
Unit 4 Signal transduction, cell cycle, mitosis, meiosis, cytokinesis
Unit 5 Gene, allele, genotype, phenotype, meiosis, Punnett square
Unit 6 DNA replication, transcription, translation, codon, mutation
Unit 7 Evolution, natural selection, Hardy-Weinberg, speciation
Unit 8 Population, community, ecosystem, biodiversity, symbiosis
Essential Diagrams to Memorize
  • ๐ŸงฌDNA Replication Fork: Leading/lagging strands, helicase, polymerase
  • Cellular Respiration Overview: Glycolysis → Krebs → ETC
  • ☀️Photosynthesis: Light reactions and Calvin cycle
  • ๐ŸงซMitosis Stages: PMAT (Prophase, Metaphase, Anaphase, Telophase)
  • ๐ŸงฌMeiosis: Crossing over, independent assortment

Study Tip for Quick Reference

Draw diagrams from memory daily—visual recall is crucial for the exam.

Practice exam questions and study materials
๐Ÿ“

Practice Questions & Sample Problems

Sample MCQs and FRQs to test your understanding of key concepts.

Sample MCQ: Hardy-Weinberg Equilibrium

In a population of 1000 individuals, 360 show the recessive phenotype. Assuming Hardy-Weinberg equilibrium, what is the frequency of the recessive allele (q)?

Answer: q² = 360/1000 = 0.36, so q = √0.36 = 0.6
Explanation: In Hardy-Weinberg, q² represents the frequency of homozygous recessive individuals.
Sample FRQ: Cellular Respiration

Describe the role of oxygen in cellular respiration and explain what happens when oxygen is unavailable.

Sample Response: Oxygen serves as the final electron acceptor in the electron transport chain, allowing oxidative phosphorylation to produce ATP. Without oxygen, cells undergo fermentation, regenerating NAD⁺ for glycolysis but producing only 2 ATP per glucose molecule instead of ~32.
Sample MCQ: Photosynthesis

Which of the following occurs in the Calvin cycle but NOT in the light-dependent reactions?

Correct Answer: Carbon fixation (CO₂ is incorporated into organic molecules)
Explanation: The Calvin cycle fixes carbon, while light reactions produce ATP and NADPH.
Calendar and important dates for AP Biology exam
๐Ÿ“…

Important Dates: 2025-2026 AP Biology Timeline

Key deadlines and dates for the AP Biology exam cycle.

2025-2026 AP Exam Calendar

November 2025 AP Registration Opens
March 2026 Late Registration Deadline
May 12, 2026 AP Biology Exam Date (Morning Session)
July 2026 Score Release (Digital Reports)
August 2026 College Credit Decisions
Warning signs and common errors to avoid
⚠️

Common Mistakes & How to Avoid Them

Frequent errors from Chief Reader reports and student experiences.

Science Vomit: Writing everything you know instead of addressing the specific question. Solution: Read prompts carefully and answer only what's asked.
Triple-Codon Error: Forgetting to divide nucleotides by 3 when calculating amino acids. Solution: Always remember: 3 nucleotides = 1 codon = 1 amino acid.
Confusing Mitosis vs. Meiosis: Saying mitosis produces genetic variation. Solution: Only meiosis creates variation through crossing over and independent assortment.
Hardy-Weinberg Misconception: Thinking deviation from H-W proves evolution. Solution: Must connect to specific mechanisms (selection, drift, etc.).
Checklist and preparation items for exam day

Exam Day Checklist

Essential items and preparation for test day success.

What to Bring
  • ๐Ÿ†”Valid photo ID (school ID, driver's license, passport)
  • ๐Ÿ“ฑFully charged device with Bluebook app installed
  • ✏️Several #2 pencils and erasers (for FRQ section)
  • ๐ŸงฎApproved calculator (if needed, though not required)
  • ๐Ÿ’งWater bottle and snacks (check testing center rules)
What NOT to Bring
  • Cell phones (except for Bluebook)
  • Notes, textbooks, or study materials
  • Highlighters, colored pencils, or correction fluid
  • Dictionaries or translation devices
Day-Before Preparation
  • Arrive 30 minutes early at testing center
  • ๐Ÿ˜ดGet adequate sleep (avoid cramming)
  • ๐Ÿฝ️Eat a good breakfast with protein and complex carbs
  • ๐Ÿง Light review of formulas and key concepts
Memory aids and mnemonic devices for biology
๐Ÿง 

Mnemonic Devices & Memory Aids

Popular mnemonics used by AP Biology students worldwide.

PMAT: Prophase, Metaphase, Anaphase, Telophase (mitosis stages)
OIL RIG: Oxidation Is Loss, Reduction Is Gain (electron transfer)
Please Call Me To Order Fresh Green Salad: Prophase I, Crossing over, Metaphase I, Telophase I, Prophase II, Metaphase II, Anaphase II, Telophase II (meiosis)
CHOPKINS CaFE: C₆H₁₂O₆ + 6O₂ → 6CO₂ + 6H₂O + energy (photosynthesis vs. respiration)
LEAF: Light-dependent reactions, Electron transport, ATP synthesis, FADH₂ (photosynthesis components)
Chart showing exam weighting by unit
๐Ÿ“Š

AP Biology Exam Weighting by Unit

Understanding which units carry the most weight on the exam.

Unit Exam Weight Priority Level
Unit 7: Natural Selection 13-20% ๐Ÿ”ด Highest Priority
Unit 3: Cellular Energetics 12-16% ๐Ÿ”ด High Priority
Unit 6: Gene Expression 12-16% ๐Ÿ”ด High Priority
Unit 1: Chemistry of Life 6-9% ๐ŸŸก Medium Priority
Unit 2: Cell Structure 10-13% ๐ŸŸก Medium Priority
Unit 4: Cell Communication 10-15% ๐ŸŸก Medium Priority
Unit 5: Heredity 8-11% ๐ŸŸก Medium Priority
Unit 8: Ecology 10-15% ๐ŸŸก Medium Priority
Study schedule and timeline planning
๐Ÿ“…

Sample 12-Week Study Schedule

A structured timeline for comprehensive AP Biology preparation.

Weeks 1-4: Foundation Building

Week 1 Units 1-2: Chemistry & Cell Structure
Week 2 Unit 3: Cellular Energetics (focus on enzymes)
Week 3 Units 4-5: Cell Communication & Heredity
Week 4 Unit 6: Gene Expression & Regulation

Weeks 5-8: Deep Dive & Practice

Week 5 Unit 7: Natural Selection (heavy focus)
Week 6 Unit 8: Ecology + Lab Review
Week 7 Science Practices & Math Skills
Week 8 Full Practice Exam + Weak Area Review

Weeks 9-12: Refinement & Mastery

Week 9 Targeted Practice: Weak Units
Week 10 FRQ Writing Practice
Week 11 Second Full Practice Exam
Week 12 Final Review & Confidence Building
Celebration and success stories from students
๐ŸŽ‰

Success Stories & Score Improvement Tips

Real student experiences and strategies that led to success.

From 2 to 5: "I focused on the labs and Science Practices. Understanding experimental design made FRQs much easier." - Sarah, 2024
From 3 to 5: "Daily practice with Hardy-Weinberg and water potential calculations. Don't underestimate the math!" - Miguel, 2024
From 4 to 5: "Drew every diagram from memory weekly. Visual recall was key for the exam." - Emma, 2024

Common Success Factors

  • Consistent daily practice (even 30 minutes)
  • Understanding over memorization
  • Mastering Science Practices 2 and 6
  • Regular full-length practice exams
  • Seeking help early for difficult concepts
Printable checklists and study trackers
๐Ÿ“‹

Printable Study Checklists

Text-based checklists for tracking your AP Biology progress.

Unit Completion Checklist
[ ] Unit 1: Chemistry of Life - Water properties, macromolecules [ ] Unit 2: Cell Structure - Prokaryotes vs eukaryotes, organelles [ ] Unit 3: Cellular Energetics - Enzymes, respiration, photosynthesis [ ] Unit 4: Cell Communication - Signal transduction, cell cycle [ ] Unit 5: Heredity - Meiosis, Mendelian genetics, inheritance patterns [ ] Unit 6: Gene Expression - Central dogma, regulation, biotechnology [ ] Unit 7: Natural Selection - Evolution, Hardy-Weinberg, speciation [ ] Unit 8: Ecology - Populations, communities, energy flow
Science Practices Mastery
[ ] Practice 1: Concept Explanation - Explain processes in context [ ] Practice 2: Visual Representations - Analyze graphs/diagrams [ ] Practice 3: Questions & Methods - Design experiments [ ] Practice 4: Representing Data - Create proper graphs [ ] Practice 5: Statistical Tests - Chi-square, error bars [ ] Practice 6: Argumentation - Support claims with evidence
Lab Investigations Review
[ ] Lab 1: Artificial Selection - Understand selective pressure [ ] Lab 2: Hardy-Weinberg - Mathematical modeling [ ] Lab 3: BLAST - DNA sequence comparison [ ] Lab 4: Diffusion/Osmosis - Cell transport factors [ ] Lab 5: Photosynthesis - Light and energy capture [ ] Lab 6: Cellular Respiration - Metabolic rate factors [ ] Lab 7: Cell Division - Mitosis stimulation [ ] Lab 8: Transformation - Bacterial genetic modification [ ] Lab 9: Restriction Analysis - DNA visualization [ ] Lab 10: Energy Dynamics - Trophic level transfers [ ] Lab 11: Transpiration - Environmental water loss [ ] Lab 12: Fruit Fly Behavior - Taxis vs kinesis [ ] Lab 13: Enzyme Activity - Reaction conditions
Dictionary and glossary of biology terms
๐Ÿ“–

AP Biology Glossary

Essential terms and definitions for quick reference.

A-C
Active Transport: Movement of substances against concentration gradient using ATP Allele: Alternative forms of a gene Amino Acid: Building blocks of proteins ATP: Adenosine triphosphate, energy currency of cells Autotroph: Organism that produces its own food (photosynthesis) Biotechnology: Use of living systems to develop products Calvin Cycle: Light-independent reactions of photosynthesis Cell Cycle: Series of events from cell formation to division Centromere: Region where sister chromatids attach Chloroplast: Organelle where photosynthesis occurs Chromosome: DNA molecule containing genetic information Codon: Three-nucleotide sequence specifying amino acid
D-H
Dehydration Synthesis: Formation of polymers by removing water Denaturation: Loss of protein structure due to environmental stress Diffusion: Movement of molecules from high to low concentration DNA: Deoxyribonucleic acid, genetic material Dominant: Allele that masks expression of recessive allele Ecosystem: Community of organisms plus abiotic environment Electron Transport Chain: Series of protein complexes for ATP production Endocytosis: Process of taking materials into cell via vesicles Enzyme: Biological catalyst that speeds up reactions Evolution: Change in allele frequencies over time Exocytosis: Process of releasing materials from cell via vesicles Fermentation: Anaerobic respiration producing lactic acid or ethanol Fossil Record: Preserved remains of ancient organisms Gene: Unit of heredity, segment of DNA Genetic Drift: Random changes in allele frequencies Genotype: Genetic makeup of an organism Glycolysis: First stage of cellular respiration, occurs in cytosol Heterotroph: Organism that consumes other organisms for energy Homeostasis: Maintenance of stable internal environment Homozygous: Having two identical alleles
I-P
Independent Assortment: Random distribution of homologous chromosomes Innate Immunity: Non-specific defense mechanisms Interphase: Period between cell divisions (G1, S, G2) Krebs Cycle: Second stage of cellular respiration, produces electron carriers Light-Dependent Reactions: Photosynthesis stage requiring light Meiosis: Cell division producing gametes with half chromosome number Mendelian Genetics: Principles of inheritance discovered by Gregor Mendel Metaphase: Stage where chromosomes align at cell equator Mitochondria: Organelles where cellular respiration occurs Mitosis: Cell division producing identical daughter cells Mutation: Change in DNA sequence Natural Selection: Differential survival and reproduction Nucleotide: Building block of nucleic acids Osmosis: Diffusion of water across selectively permeable membrane Phenotype: Observable characteristics of an organism Photosynthesis: Process converting light energy to chemical energy Polymerase Chain Reaction (PCR): Technique to amplify DNA Population: Group of same species in same area Primary Productivity: Rate of energy production by autotrophs Punnett Square: Diagram showing possible genotypes from cross
R-Z
Recessive: Allele whose expression is masked by dominant allele Replication: Process of DNA copying before cell division RNA: Ribonucleic acid, involved in protein synthesis Sexual Selection: Selection based on mating success Speciation: Formation of new species Stabilizing Selection: Selection favoring intermediate traits Symbiosis: Close relationship between different species Taxonomy: Science of classifying organisms Telophase: Final stage of mitosis/meiosis Transcription: Synthesis of RNA from DNA template Translation: Synthesis of protein from mRNA template Vestigial Structure: Reduced structure with no current function

๐Ÿงฌ AP Biology Mastery Overview

Big Ideas: Evolution, Energy, Information, Systems
Units: 8 comprehensive units with detailed content
Science Practices: 6 skills assessed throughout exam
Labs: 13 investigations requiring hands-on understanding
Math: Formulas for Hardy-Weinberg, water potential, statistics
Exam: Digital MCQs + hybrid FRQs, 50% each
Strategies: Active learning, time management, practice
Resources: College Board materials, textbooks, online tools